The world's largest wildlife crossing over the 101 Freeway in Agoura Hills is set to open Dec. 2, pending weather delays. The $114 million project aims to reconnect isolated mountain lions in the Santa Monica Mountains, threatened by inbreeding, with populations in the Simi Hills. Construction challenges include compacting clay-rich soil, which becomes slick when wet, potentially delaying completion. The crossing is expected to improve genetic diversity and species survival.